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¡¾2608¡¿He is such a big guy

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    While eating, I chatted with Teacher Tan about scientific research.

    Teacher Tan is an expert in laparoscopy, general surgery, and gastrointestinal surgical oncology.  Dr. Tan's traditional surgery and laparoscopic surgery are both top-notch, and his extra-operative treatment plans for tumor patients are also top-notch.

    It would be ridiculous to imagine that the scope of academic research that Teacher Tan can do is limited to laparoscopy.  For example, Brother Xian rarely performs heart transplant surgeries, but he does research on assistive devices for end-stage cardiac treatment.

    For surgeons, surgery is an advantage when engaging in scientific research, as it can conduct research on various surgeries.  On the other hand, in the field of basic disciplines, surgeons have advantages. This mainly refers to the advantages of pathological specimens obtained by surgeons.

    It is too easy for surgeons to capture surgical pathology specimens of various patient tumors during surgery.  Unlike other departments, it is difficult to get a pathological specimen of your own choice.  The specimens obtained by medical laparoscopy are limited in scope and far inferior to those obtained by surgery.  In this way, you will find that surgeons who are the masters of basic research can be as good as or even better than physicians and pathologists.

    Teacher Tan happens to be such a big boss.

    Speaking specifically of the topic studied by Teacher Tan, we can talk about a large class of star anti-tumor drugs that have become famous since entering the 21st century: targeted drugs.

    Targeted drugs are like arrows aimed at the "protrusions" of tumors. Compared with chemotherapy drugs, they are like spraying pesticides when attacking tumors. They are more precise and avoid damaging healthy human tissues. They are warmly welcomed by doctors and patients.  The advantage of targeted drugs is accuracy, and the accuracy of targeted drugs is based on the target. Finding the target of targeted drugs has naturally become a top priority for scientific researchers.

    The study of targets is essentially inseparable from the study of tumor pathogenesis.

    The pathogenesis of tumors is complex, and there are many links and substances involved in tumor pathogenesis, all of which can theoretically become targets.  For example, the most common substance receptors, transporters, enzymes, ion channels, genes, etc., many of which are basic topics that have been studied.  There is a relatively new research topic here that has only been discovered and proposed in recent years, called microRNA.

    Microran, to put it simply, can be said to be a substance of intestinal flora.  Good microRNA can inhibit tumor tissue after being absorbed by humans.  Bad microRNAs can promote the growth of tumor tissue.  According to this principle, if medical oncology studies the former, it can be made into a tumor inhibitor.  If you want to deal with the bad things behind, targeted drugs that can be used as a "sudden" attack are most suitable.

    Medical science has discovered that just suppressing tumors is not as good as killing them.  How cutting-edge are microRNA-targeting drugs? According to the information that Xie Wanying knows from people who came back from the future, they are a new trend in targeted drugs in the future.

    No matter what, as mentioned before, to make targeted drugs, we must first find the target, and to make RNA-targeted drugs, we must find microRNAs.  The key topic of Teacher Tan is the study of colon cancer microRNA, and a brand-new microRNA was discovered in a wide range of colon cancer specimens. Theoretically, it can become the target of new targeted drugs for colon cancer. It is the leading tumor in the world.  It is a key area at the forefront of scientific research.

    Teacher Tan¡¯s research project is so cutting-edge, Xie Wanying must have said that she can¡¯t dictate the teacher¡¯s research.

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